Esya in the Press​

Esya in the Press​

Esya has been featured by widely recognized national and international news outlets and prestigious science publications.

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Could This Blood Test Revolutionise How Dementia and Other Neurodegenerative Diseases Are Diagnosed?

Every 3.2 seconds someone in the world is diagnosed with dementia. 

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Yamuna Krishnan creates tiny machines from DNA for early and accurate disease diagnosis

Yamuna Krishnan is a professor of chemistry at the University of Chicago and the co-founder of Esya Labs.

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Yamuna Krishnan’s Goal: Find Drugs for Neurodegenerative Diseases

Her company, Esya Labs, is developing DNA nanodevices that track drug responses, screen for new therapies and more

image of doctor

Yamuna Krishnan’s Goal: Find Drugs for Neurodegenerative Diseases

Her company, Esya Labs, is developing DNA nanodevices that track drug responses, screen for new therapies and more

esya subcellular diagnostics

Esya Labs Provides Novel Research Assays to Accelerate Drug Discovery Efforts

Esya Labs, which is developing several ground-breaking novel research assays, today has announced that Novartis is among the first companies to use its technology. 

esya subcellular diagnostics

Esya Labs Provides Novel Research Assays to Accelerate Drug Discovery Efforts

Esya Labs, which is developing several ground-breaking novel research assays, today has announced that Novartis is among the first companies to use its technology. 

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Esya Labs and HeioThera Receive $250,000 Investment from the George Shultz Innovation Fund

The 2021 Spring Cohort of the George Shultz Innovation Fund has invested $250,000 in both Esya Labs and HeioThera – and this number will increase as they solidify additional funding.

dr georgiou researching

From home-grown to international: New companies move into the Imperial Incubator

New residents at the Imperial Incubator have come from as far afield as Boston and as close to home as the South Kensington campus.

doctor yamuna krishnan

This UChicago Technology Could Transform Diagnoses of Cellular Diseases

In the human body, the lysosome is often referred to as the stomach of the cell — eating up and recycling old cellular material.

Discoveries Made With Esya's Technology
Esya's technology has been featured in many influential publications in leading scientific journals

A DNA nanomachine that maps spatial and temporal pH changes inside living cells

DNA nanomachines are synthetic assemblies that switch between defined molecular conformations upon stimulation by external triggers. 

A pH-correctable, DNA-based fluorescent reporter for organellar calcium

It is extremely challenging to quantitate lumenal Ca2+ in acidic Ca2+ stores of the cell because all Ca2+ indicators are pH sensitive, and Ca2+ transport is coupled to pH in acidic organelles. 

Two DNA nanomachines map pH changes along intersecting endocytic pathways inside the same cell

DNA is a versatile scaffold for molecular sensing in living cells, and various cellular applications of DNA nanodevices have been demonstrated. 

A DNA nanomachine chemically resolves lysosomes in live cells

Lysosomes are multifunctional, subcellular organelles with roles in plasma membrane repair, autophagy, pathogen degradation and nutrient sensing. 

DNA nanodevices map enzymatic activity in organelles

Cellular reporters of enzyme activity are based on either fluorescent proteins or small molecules. 

High lumenal chloride in the lysosome is critical for lysosome function

Lysosomes are organelles responsible for the breakdown and recycling of cellular machinery.

Discoveries Made With Esya's Technology
Esya’s recent press

If you crave challenges, there's no better place to be

Esya is a dynamic company operating at the intersection of biochemistry, technology and medicine. ​If you crave challenges and the chance to see your work impact the millions of lives touched by Alzheimer’s disease, there’s no better place to be.