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New Biomarkers to

Accelerate Drug Development & Track Disease Progression

AI driven In-cell Molecular Analytics and Diagnostics

Esya's DNA probes can ratiometrically quantify ions within endocytic organelles such as Endosomes & Lysosomes, for diseases such as COVID-19, Lysosomal Storage Disorders & Alzheimer's Disease

Who We Are

A precision biomarker company providing groundbreaking molecular insights to facilitate drug discovery, diagnostics, and personalized medicine, by profiling ion signatures within key organelles.  

 

By chemically profiling various biological markers, such as lysosomal ion signatures, our technologies can help decode the underpinnings of a number of different diseases, as well as test potential drug treatments and therapies. 

Lab Experiment
 
 
 

Innovative Technology

In-Cell Ion measurement

Our nanodevices are DNA sensors made of DNA filaments knitted-together to hold measuring devices to ratiometrically quantify ions for specific chemicals:

  • I-switch (pH)

  • Clensor (Cl-)

  • CalipHluor (Ca2+ & pH)

  • ChloropHore (pH & Cl-)

  • Enzyme detection

Quantifiable Measurement within Organelles

Different versions of our nanodevices target different organelles for precision measurement within live cells:

  • Early endosome

  • Late endosome

  • Lysosome

  • Recycling endosome

  • Golgi

Esya's non invasive Patient driven biomarkers

By chemically profiling various biological markers, such as lysosomal ion signatures, our technologies can help decode the underpinnings of a number of different diseases, as well as test potential drug treatments and therapies.

Subcellular Imaging

  • Patient Cells either normal or manifesting a disease

  • Esya's proprietary Probes added to the cell culture, either individually or with High throughput screening

  • Cells imaged for ratiometric analysis

Data Science-Based, AI-Enabled Analytics

  • Imaged cells analysed using custom built Esya Analytics

  • Esya's Analytics are proprietary machine learning based Algorithms enhanced with Big data

  • In-cell reaction and biomarker reports with quantifiable measurements

Disease Modeling and Therapeutic Insights

  • Measure and monitor disease progression

  • Non-invasively quantify a patient's response to a treatment

  • Reveal the efficacy and specificity of a drug

  • Phenotype diseases to discover new therapeutics

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Media & Press Updates

 
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